Bone structure and metabolism

Bone structure, or the skeleton, is fundamental for providing support to the organism. The bones of the skeleton perform various functions, including mechanical support for joints, tendons, and ligaments, protection of vital organs, regulation of calcium and phosphate levels in the body, and production of blood cells. Bone is a constantly changing tissue, undergoing renewal and repair processes throughout life through bone remodeling. Most bone diseases arise due to alterations in this remodeling process, affecting the structure, mechanical strength, and mineral balance of the bone, manifesting in symptoms such as pain, deformity, fractures, and imbalances in calcium and phosphate levels in the body.

A wide variety of proteins and enzymes participate in the bone remodeling process, helping to balance and direct all the metabolic processes involved. Additionally, during the remodeling process, small molecules are released into the bloodstream that can be used as markers, as they are byproducts of bone metabolic activity. Through antibodies, ELISA kits, and proteins from Abylabel, it is possible to study the signaling pathways involved in the process, as well as the biomarkers for evaluating disorders in bone structure.

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